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Effects of Seamoss on the Nervous System: A Comprehensive Review

Abstract:

Seamoss (Chondrus crispus), also known as Irish moss or carrageen moss, is a marine alga with a long history of traditional use and potential health benefits. While seamoss is recognized for its nutritional value, its effects on the nervous system remain relatively understudied. This comprehensive review aims to explore the impact of seamoss on the nervous system, including its potential neuroprotective, neuroinflammatory, and neuroregenerative properties. By synthesizing available evidence from in vitro, animal, and clinical studies, this review provides insights into the potential effects of seamoss on nervous system health and function.

Introduction:

The nervous system plays a vital role in regulating various physiological processes and maintaining overall well-being. Understanding the potential effects of natural substances, such as seamoss, on the nervous system is essential for exploring its neurobiological impact. This review seeks to investigate the influence of seamoss on the nervous system, including its effects on neuroprotection, neuroinflammation, and neuroregeneration.

Methods:

A comprehensive literature search was conducted using electronic databases, including PubMed, Scopus, and Web of Science. Studies investigating the effects of seamoss on the nervous system, including in vitro, animal, and clinical studies, were included. This review synthesizes findings from these studies to provide insights into the potential impacts of seamoss on nervous system health and function.

Results:

Seamoss contains various bioactive compounds, including polysaccharides, peptides, and minerals, which have been associated with potential effects on the nervous system. Polysaccharides found in seamoss, such as carrageenans, have demonstrated neuroprotective properties in in vitro and animal models by reducing oxidative stress, preventing neuronal damage, and enhancing neuronal survival. These polysaccharides may also modulate neuroinflammatory processes by inhibiting pro-inflammatory cytokines and reducing microglial activation.

Furthermore, seamoss-derived peptides have shown neuroregenerative potential by promoting neurite outgrowth, neuronal differentiation, and synaptogenesis. These peptides may enhance neuroplasticity and contribute to neural repair and regeneration processes in the nervous system. Seamoss is also rich in minerals like iodine and magnesium, which are essential for proper nervous system function and may play a role in neurotransmission, neuronal signaling, and neuroprotection.

Conclusion:

Although research specifically focused on the effects of seamoss on the nervous system is limited, preliminary evidence suggests its potential neuroprotective, anti-neuroinflammatory, and neuroregenerative properties. The bioactive compounds present in seamoss, including polysaccharides, peptides, and minerals, may contribute to these effects. Further research, including well-designed human studies, is needed to elucidate the specific mechanisms underlying the effects of seamoss on the nervous system and to explore its potential therapeutic applications for neurological disorders and nervous system health.

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